Clean Room Application

Clean room definition

Cleanroom refers to the removal of pollutants in the space, including dust, microorganisms, suspended particles and chemical volatile gases, etc., and control of temperature, humidity, cleanliness, air velocity, indoor pressure, noise, vibration and lighting …Equal variables, and then get a clean working environment, if the bacteria, viruses and biological particles in the clean room are controlled, it is called a germ-free room.

The function of the clean room is that no matter how the external air conditions change, the indoor space can maintain the original cleanness, temperature and humidity and indoor pressure required by the original setting. After years of development, the industry has standardized and matured the specifications and requirements for its project planning and construction, equipment cleanliness capability, and consumable quality control. For an efficient clean room, the hardware and software architecture must be equally important. In addition to complete and detailed planning and efficient and reliable construction management in the clean room engineering design and construction, it also needs to cooperate with the completion of the construction. The education and training of the clean room encourages indoor personnel to maintain good working discipline, and at the same time implement the use and operation specifications and equipment maintenance, in order to maximize the functions of the clean room.

Function

The clean room must have the ability to effectively control the amount of particulate pollution in a specific space, and its main conditions are as follows:

Can remove dust particles in the air

Can prevent the generation of dust particles

Temperature and humidity control

Regulation of indoor pressure

Elimination of harmful gases

Air tightness of structure and compartment

Anti-static

Prevention of electromagnetic interference

Safety considerations

Energy saving considerations

  • Can remove dust particles in the air
  • Can prevent the generation of dust particles
  • Temperature and humidity control
  • Regulation of indoor pressure
  • Elimination of harmful gases
  • Air tightness of structure and compartment
  • Anti-static
  • Prevention of electromagnetic interference
  • Safety considerations
  • Energy saving considerations

What is cleanliness

In order to define the performance of various clean rooms, the number of particles of a “specific size” defined in the “specific volume” is used as a benchmark. This index is called “Cleanliness”. Take particles with a diameter of 0.5μm (micrometer) or more as an example:
Particle distribution status Space/Clean room specifications
10,000,000 – 50,000,000 pcs/m3 Outskirts
100,000,000 – 500,000,000 pcs/m3 City
100,000,000 – 1,000,000,000 pcs/m3 Indoor
0.5μm particle size, control within 3,520 particles/m3 Clean room-ISO Class 5
0.5μm particle size, controlled within 3,530 particles/m3 Clean room-FS 209E Class 100

Industry division

The application of clean room is mainly divided into ICR industrial clean room (Industrial Clean Room) and BCR biochemical and medical clean room (Biological Clean Room). According to different industries, there are different requirements for cleanliness.

ICR industrial clean room
Mainly used in semiconductor, electronics and various types of precision industries. Internationally, the cleanliness requirements of ICR industrial clean rooms mainly refer to the US Federal Standard FS-209E and Japanese Standard JIS B 9920. The US FS-209E is hereby adopted as the standard ,Correct

Industry categoryCleanliness
ISO 2ISO 3ISO 4ISO 5ISO 6ISO 7ISO 8
–209E Class
1		209E Class
10		209E Class
100		209E Class
1,000		209E Class
10,000		209E Class
100,000
ICRChip manufacturer   
Semiconductor component manufacturerFront end project  
Backstage project     
LCD manufacturer    
Hard drive manufacturer    
Precision Machinery Manufacturer   
Mask manufacturer    
Printed Circuit Board Manufacturer   

BCR biological clean room
Clean rooms/sterile rooms are mainly used in industries such as biotechnology, biochemistry, medicine, and academic research units. In addition to removing particles floating in the air, bacteria and viruses attached to dust must also be removed. Therefore, in addition to air filtration systems, Usually it must be accompanied by chemical sterilization such as ultraviolet rays. Taking the US FS-209E as the standard, the specifications for each industry are as follows:

Industry categoryCleanliness
ISO 2ISO 3ISO 4ISO 5ISO 6ISO 7ISO 8
–209E Class
1		209E Class
10		209E Class
100		209E Class
1,000		209E Class
10,000		209E Class
100,000
BCRPharmaceutical manufacturerInjection filling area     
Pharmacy packaging area     
hospitalSterile treatment room    
Sterile operating room     
Food processing manufacturerLong-term fresh milk     
Fresh vegetables, fruits, bento, bread     
Animal laboratorySterile animal treatment room     
SPF animals    

Pollution source

In order to effectively maintain the cleanliness of the clean room, in addition to the planning and installation of hardware equipment, a good management system is also required. Among them, the management of pollution sources is the most important. The pollution sources are divided into two categories: “external pollution and internal pollution”. Exploring according to the operators, raw materials, equipment and all the objects in the clean room, the experimental data shows that “people” are the largest source of pollution in the clean room (about 80%). When the workers enter and leave the clean room, the dust increases significantly If the operator moves, the cleanliness will immediately deteriorate, so the operator must wear dust-free clothes, masks, gloves, etc. to avoid infection. The main pollution sources of the clean room are as follows: